# HFMSE Improvements and SPINRAZA Benefits
Keywords: HFMSE scale, SPINRAZA, SMA, motor function, clinical trials, independence, adverse events

> This page provides information about the HFMSE scale, its relevance in evaluating motor function in SMA patients, and the potential benefits of SPINRAZA treatment. It also highlights tools for assessment and reporting procedures for adverse events.

## Details
- [HFMSE Improvements](#): The HFMSE scale evaluates motor function in SMA patients, with improvements indicating gains in independence and daily activities.
- [2-Point Gain on HFMSE Scale](#): A 2-point increase reflects a new activity or improvement in two activities, showing meaningful progress for patients and caregivers.
- [What is the HFMSE Scale?](#): The HFMSE scale measures 33 activities, scored from 0 to 2, with a maximum score of 66. A 3-point change is considered clinically significant.
- [Assessment Tools](#): Tools for evaluating motor functions in SMA patients are available for download, including instructions and score sheets.
- [Adverse Event Reporting](#): Guidance on reporting adverse events in the UK and Ireland, with contact details for Biogen and regulatory authorities provided.