# SPINRAZA Administration and Information Keywords: SPINRAZA, nusinersen, intrathecal administration, lumbar puncture, cerebrospinal fluid, SMA, 5q SMA, adverse events > This page provides detailed information about SPINRAZA (nusinersen), its administration process, and key considerations for healthcare professionals treating patients with 5q SMA. ## Details - [SPINRAZA Overview](#): SPINRAZA is a treatment for 5q SMA administered intrathecally via lumbar puncture. - [Administration Guidelines](#): Detailed steps for preparing and administering SPINRAZA, including aseptic techniques and monitoring cerebrospinal fluid. - [Initiation of Treatment](#): SPINRAZA treatment should begin immediately after SMA diagnosis confirmation. - [Administration Techniques](#): Techniques such as ultrasound, CT, and X-rays can be used to guide administration. - [Adverse Event Reporting](#): Instructions for reporting adverse events in the UK and Ireland, including contact details for Biogen. - [References](#): Supporting references and documentation related to SPINRAZA and SMA.