# Family Planning Keywords: family planning, multiple sclerosis, pregnancy, breastfeeding, relapse rate, disease-modifying therapy, interferon beta, PLEGRIDY > This page provides information for healthcare professionals about family planning considerations for patients with multiple sclerosis (MS), including the use of PLEGRIDY during pregnancy and breastfeeding, relapse rate changes, and patient support options. ## Details - [Family Planning](#): PLEGRIDY can be used during breastfeeding and may be considered during pregnancy if clinically needed, with limited data on risks during the first trimester. - [PLEGRIDY SmPC Recommendations](#smpc): Provides detailed guidance on the use of PLEGRIDY during pregnancy and breastfeeding, based on clinical and post-marketing data. - [Why is Family Planning in MS Such a Big Topic?](#relapse): Discusses the prevalence of MS in women of childbearing age and the impact of MS-related concerns on family planning decisions. - [Relapse Rate and Pregnancy](#relapse): Explains how relapse rates decrease during pregnancy, especially in the third trimester, but may rebound postpartum, emphasizing the importance of treatment planning. - [References and Abbreviations](#): Includes definitions for terms like ARR, DMT, and SmPC, and lists references supporting the content.