# Efficacy Keywords: PLEGRIDY, RRMS, efficacy, ADVANCE study, NEDA, MRI, ARR, disability progression > This page provides detailed information about the efficacy of PLEGRIDY for treating Relapsing Remitting Multiple Sclerosis (RRMS), including clinical trial results, long-term outcomes, and comparative data. ## Details - [Clinical and Radiological Pivotal Data](#pivotaldata): Overview of significant clinical and neuroradiological results from year 1 of the ADVANCE study. - [NEDA Data](#neda): Information on the percentage of patients achieving No Evidence of Disease Activity (NEDA) over 4 years. - [Comparison Data](#comparison): Comparative analysis of PLEGRIDY's efficacy versus glatiramer acetate in terms of relapse rate and disability progression.